Flordis Premular For PMS (Vitex) 30 Tablets

Flordis Premular For PMS (Vitex) 30 Tablets is a natural medicine clinically proven for the symptomatic relief of premenstrual syndrome (PMS); including symptoms of irritability, anger, headache, bloating and breast tenderness.1,2 Vitex agnus castus (Chaste tree) has a long history of use for hormonal conditions and menstrual complaints.

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  • Premular provides relief from physical and mental PMS symptoms

    If you are suffering from the aches and angst of premenstrual syndrome (PMS), you are not alone. It is estimated that 40% of women will be significantly affected by PMS symptoms at some time during their life, and 7% severely so.1

    The good news is that you can do something about it: Premular is an evidence-based natural medicine that is clinically proven to relieve a range of physical and mental PMS symptoms including:

    • Mood swings and irritability or anger
    • Bloating and breast fullness
    • Cramps and headaches

    Premular provides sustained relief over time,1-4 is well-tolerated and its once-a-day dosing makes it convenient to take.

    Three published Premular clinical trials show significant relief in PMS symptoms for women taking Premular over a 3-month period, and lasting for 3 cycles even after therapy has ceased.2,3 

    What makes Premular different?

    Premular contains a specific extract of the Vitex agnus-castus (Chaste tree) referred to as Ze 440. This extract is exclusive to Premular and has demonstrated effectiveness in the reduction of PMS symptoms. This was shown in clinical trials, including a double-blind placebo controlled study published in the British Medical Journal.2

    One recent publication confirmed that the dose used in Premular is the optimal dose for the relief of PMS symptoms.3

    Premular is manufactured in Switzerland according to careful production methods. This ensures  a consistently reliable medicine, which is the same medicine used in clinical trials. Premular has also been assigned a ‘well established medicinal use status’ a status based on its history, evidence and excellent tolerability.5,6

  • Each tablet of Premular contains: . 

     Extract equivalent to dry Vitex agnus-castus fruit 180mg


    Vitex has a long history of traditional use  as a tonic for the reproductive system.

    Premular contains a clinically trialled extract (Ze 440) of the herb Vitex agnus-castus, also known as Chaste tree.

  • Recommended Dosage and Directions

    Adults: 1 tablet per day

    For best results take Premular for a minimum of 3 months. 


    Premular has a documented safety profile and is well tolerated.

    FAQs About Premular

    • Is Premular likely to have any side effect?

    Premular is generally very well tolerated and not expected to cause unwanted side effects. However, in rare cases occasional itching of the skin may occur and, at the start of the dosage only, certain isolated premenstrual symptoms may be slightly increased. These symptoms should resolve without discontinuing Premular. If you are concerned you are experiencing side effects from Premular, it is important to speak with your healthcare practitioner. 

    • Is Pemular safe for use in pregnancy and lactation?

    Premular is not indicated for use during pregnancy or while breastfeeding. Although there are no reported safety concerns, there are no published studies to establish safety for the use of Premular during pregnancy or while breastfeeding. It is important to speak with a healthcare professional if you have specific questions or concerns. 

    • How does Pemular differ to the chaste tree products?

    Premular contains a clinically proven extract of Chaste tree (Vitex agnus-castus) referred to as Ze 440. Exclusive to Premular, Ze 440 has demonstrated  to have successful outcomes in clinical trials, including a study suggesting Premular contains an optimal dose for the relief of a range of PMS symptoms.


    When taking Premular, you can be confident you are receiving a consistent natural medicine that has been tested in clinical trials.

    • Does Premular contain lactose?

    Premular contains a very small amount of lactose (40 mg) in each tablet. 

    • Will Premular affect the ability to drive and operate machinery?

    Premular tablets have no known adverse effects in these situations. 

    • Is Premular likely to interact with any medications?

    There are no expected drug interactions with Premular. It is important to discuss taking Premular with a healthcare professional if you are on prescription medications. 

    • Is Premular suitable for children and adolescent? 

    Premular is suitable for adults and adolescents.

    • How long should Premular be take for? 

    The minimum recommended treatment period is 3 months. Depending on the condition and symptoms, Premular can be continued long term. It is important to speak with a healthcare professional if you have any questions about taking Premular. 

    • When should I start  taking Premular in my cycle?

    Dosing should be started  at the start of a menstrual cycle (i.e. within the first few days of menstrual bleeding) and continue throughout the month.

    • Does Premular contain any allergens?

    Premular has no added gluten, wheat soy, sugar, yeast, salt, artificial colours or preservatives. 

    • Should Premular be stopped before surgery?

    It is important to discuss this with your healthcare professional, including anaesthetist and surgeon. 


    1. Lentz GM, et al (eds). Comprehensive Gynecolgy 6th Ed 2012. Elsevier Mosby. Chap 36 pp 797-803 2.Schellenberg R et al. BMJ 2001;322:134-137 3. Schellenberg R, et al. Phytomedicine. 2012; pii: S0944-7113(12)00280-2 4. Berger D et al Arch Gynecol Obstet 2000;264:150-153  5. Committee on Herbal Medicinal Products (HMPC). EMEA/HMPC/144003/2009 6. Committee on Herbal Medicinal Products (HMPC). EMA/HMPC/144006/2009 7. Dickerson LM, et al. Am Fam Phys. 2003;67:1743-52 

    Some of this research was conducted using funding provided by Max Zeller Soehne AG, the manufacturer of this product. 

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